Neuroscience methods for physiological psychology

Aim: to study relationship between brain and behaviour

1. Neuroanatomical & Neurochemical methods:

• Cytoarchitectonics (Brodmann areas)-study of cellular composition of the body's tissues under the microscope
• staining, immunocytochemistry & autoradiography

2. Recording & stimulating neural activity:

• non-invasive methods to study living human brain-TMS, EEG, ERPs and fMRI
• micro- and macro-electrodes in animal studies

3. Effects of brain lesions:

• pathology leading to human brain lesions
• virtual lesions induced by TMS
• experimental ablation in animal models with stereotaxic guidance)
• cooling induces reversible lesion

Neuroscience techniques-serving for study of relationship between brain and behaviour
Is there any ideal method that spatial resolution=cellular level, temporal resolution=millisecond scale,  study the whole brain simultaneously and being non-invasive at the same time? NO!
Match existing methods, which all of them come with certain limitations, to the research question.




How to us electrophysiolocial methods for cognitive neuroscience?
>responses to multiple repeated events occurring with fixed latency (time-locked)
>non-time-locked responses to events (oscillations of specific frequency)
>Events are experimentally controlled, e.g. a sensory stimulus or a task instruction occurring at a defined time point